AOD-9604
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AOD-9604

Extensively Studied

First effectsWeek 1-2
Full benefitsWeek 8-12
Category 2

AOD-9604 is a modified 17-amino acid fragment of human growth hormone (hGH 176-191) with an added N-terminal tyrosine. It stimulates fat burning and blocks new fat storage without the growth-promoting effects of full hGH. Unlike intact growth hormone, AOD-9604 does not increase IGF-1, affect glucose metabolism, or bind to the GH receptor.

How it works

AOD-9604 stimulates fat burning and blocks new fat storage by activating fat-burning receptors, without binding to the GH receptor. This selective action provides fat loss effects without the high blood sugar, insulin resistance, or unwanted cell growth associated with full growth hormone.

Key benefits

  • Stimulates fat burning and blocks new fat storage without growth hormone side effects
  • Does not increase IGF-1 or affect glucose metabolism
  • Shows promise for cartilage repair and joint health
  • Well-studied safety profile with no impact on insulin or blood sugar

Related goals

Protocols

ProtocolDoseFrequency
Fat loss250-300mcgOnce daily
Enhanced fat loss400-500mcgOnce daily
Joint support250mcgOnce daily
Conservative start200mcgOnce daily

Protocols are from published research literature. This is not medical advice. Dosing should be determined by a licensed clinician.

What to expect

Week 1-2

Minimal noticeable effects, compound building in system

Week 3-4

May notice subtle changes in body composition

Week 5-8

More noticeable fat loss, especially with diet and exercise

Week 8-12

Continued fat reduction, improved body composition

What to know

  • Generally well-tolerated in clinical trials
  • Does not affect blood glucose or insulin - safer than full hGH
  • Does not increase IGF-1 levels
  • May cause mild injection site reactions
  • Not recommended during pregnancy or breastfeeding
  • WADA prohibited substance - not for competitive athletes

Key research

Heffernan MA et al. · International Journal of Obesity · 2001
Heffernan MA et al. · American Journal of Physiology · 2000
Kwon DR et al. · Annals of Clinical and Laboratory Science · 2015
Cox HD et al. · Drug Testing and Analysis · 2015