GHK-Cu
Targeted skin improvement
Focused on the application area. Fine lines, hydration, wound healing, and skin texture. Most effective when combined with microneedling to improve skin penetration. Without microneedling, absorption is limited to the upper layers.
Topical protocols
| Protocol | Dose | Frequency |
|---|---|---|
| Daily skincare | 0.5-1% concentration | Twice daily |
| Post-microneedling | 1-2% concentration | After treatment |
| Wound healing | 1% concentration | Twice daily |
| Hair topical | 1% concentration | Daily |
Protocols are from published research literature. This is not medical advice. Dosing should be determined by a licensed clinician.
What to expect
Better skin hydration and reduced redness in application area.
Skin texture begins improving. Fine lines start softening.
Visible improvement in fine lines and skin elasticity in treated area.
Cumulative collagen building effects. Best results with consistent microneedling protocol.
What to know
- ⚠Patch test before first use to check for copper sensitivity
- ⚠Avoid application on open wounds unless directed by a clinician
- ⚠May cause skin purging (temporary breakouts) before improvement
- ⚠Store away from direct sunlight
- ⚠Limited systemic absorption without microneedling
Other ways to take GHK-Cu
How GHK-Cu works
GHK-Cu binds copper ions and delivers them to cells, activating pathways involved in collagen production, antioxidant defense, and tissue remodeling. Research shows it modulates the expression of over 4,000 genes, many related to wound healing, immune response, and inflammation. It promotes new blood vessel formation and increases production of decorin, a protein essential for skin structure.