← KPV overview
KPV
Nasal spray
Chronic sinusitis relief
Early research
First effectsWeek 1
Full benefitsWeek 4-6
Nasal KPV delivers anti-inflammatory action directly to the sinus passages for chronic sinusitis and nasal inflammation. Targets the source of sinus inflammation without systemic exposure.
Nasal spray protocols
| Protocol | Dose | Frequency |
|---|---|---|
| Chronic sinusitis | 200-400mcg | 1-2x daily |
| Acute sinus inflammation | 400mcg | 2x daily for 1-2 weeks |
Protocols are from published research literature. This is not medical advice. Dosing should be determined by a licensed clinician.
What to expect
Week 1
Reduced nasal congestion and sinus pressure.
Week 2-3
Improved breathing and reduced sinus inflammation.
Week 4-6
Significant relief from chronic sinusitis symptoms.
What to know
- ⚠Do not use if nasal passages are actively infected
- ⚠Monitor for nasal irritation with prolonged use
- ⚠Store in refrigerator after opening
- ⚠Consult healthcare provider if using other nasal medications
Other ways to take KPV
How KPV works
Enters cells and inhibits inflammatory pathways at the nuclear level, particularly NF-κB (a key inflammation switch) signaling
Key research
Dalmasso G et al. · Gastroenterology · 2008
Kannengiesser K et al. · Inflammatory Bowel Diseases · 2008
Xiao B et al. · Molecular Therapy · 2017
Land SC · International Journal of Physiology, Pathophysiology and Pharmacology · 2012
Viennois E et al. · Cellular and Molecular Gastroenterology and Hepatology · 2016
Cutuli M et al. · Journal of Leukocyte Biology · 2000