← KPV overview
KPV
Topical
Skin conditions and psoriasis
Early research
First effectsWeek 1
Full benefitsMonth 2-3
Topical KPV targets skin inflammation directly. Research shows topical KPV reduced psoriatic markers by 60%. Best for psoriasis, eczema, and localized skin inflammation where systemic treatment is not needed.
Topical protocols
| Protocol | Dose | Frequency |
|---|---|---|
| Psoriasis/eczema | 0.5-1% cream | Twice daily |
| General skin inflammation | 0.5% cream | Once daily |
| Acute skin flares | 1% cream | Twice daily |
Protocols are from published research literature. This is not medical advice. Dosing should be determined by a licensed clinician.
What to expect
Week 1
Reduced redness and irritation at application site.
Week 2-4
Visible improvement in skin inflammation and texture.
Month 1-2
Significant reduction in psoriatic markers.
Month 2-3
Sustained skin improvement with continued use.
What to know
- ⚠Patch test before first use
- ⚠For external use only
- ⚠Avoid contact with eyes and mucous membranes
- ⚠Discontinue if severe irritation occurs
Other ways to take KPV
How KPV works
Enters cells and inhibits inflammatory pathways at the nuclear level, particularly NF-κB (a key inflammation switch) signaling
Key research
Dalmasso G et al. · Gastroenterology · 2008
Kannengiesser K et al. · Inflammatory Bowel Diseases · 2008
Xiao B et al. · Molecular Therapy · 2017
Land SC · International Journal of Physiology, Pathophysiology and Pharmacology · 2012
Viennois E et al. · Cellular and Molecular Gastroenterology and Hepatology · 2016
Cutuli M et al. · Journal of Leukocyte Biology · 2000