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Goal

Better sleep

Deeper, more restorative sleep. Falling asleep faster, staying asleep longer, and waking up genuinely rested.

BETTER SLEEP · 6 compounds · Last updated Apr 2026

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6 compounds · Ranked by evidence

01

Epitalon

Epitalon is a small synthetic peptide based on a compound your pineal gland produces naturally. The two things people typically notice first: improved sleep quality (from increased melatonin production) and a general sense of cellular renewal (from telomerase activation, which maintains telomere length).

BEST FOR

longevitysleep

EVIDENCE

ROUTE

InjectionNasal sprayOral
02

DSIP

DSIP (Delta Sleep-Inducing Peptide, listed by the FDA as Emideltide) is a short, naturally occurring peptide first isolated from the blood of sleeping rabbits in 1974. It's the oldest compound on the FDA's July 2026 review agenda by date of discovery.

BEST FOR

sleep

EVIDENCE

ROUTE

InjectionNasal spray
03

CJC-1295 (without DAC)

CJC-1295 without DAC (also called Mod GRF 1-29) is a short-acting peptide that tells your pituitary gland to release more growth hormone. It works with your body's natural rhythm, triggering growth hormone in pulses rather than flooding your system with a constant supply.

BEST FOR

sleeprecovery

EVIDENCE

ROUTE

Injection
04

Ipamorelin

Ipamorelin is a selective peptide that tells your pituitary gland to release more growth hormone. It has a clean side-effect profile with minimal impact on cortisol and prolactin levels, making it well suited for body composition, recovery, and anti-aging applications.

BEST FOR

sleeprecovery

EVIDENCE

ROUTE

Injection
05

Sermorelin

Sermorelin is a peptide that signals your pituitary gland to produce more growth hormone. It was FDA-approved in 1997 for children with growth hormone deficiency and was taken off the market in 2008 for manufacturing reasons, not safety concerns.

BEST FOR

sleepbody composition

EVIDENCE

ROUTE

InjectionNasal spray
06

Selank

Selank is an anti-anxiety and cognitive peptide developed by the Russian Academy of Sciences, where it's been approved as a prescription medication. It's a synthetic peptide derived from tuftsin, a naturally occurring immune-regulating peptide.

BEST FOR

cognitionsleep

EVIDENCE

ROUTE

Nasal sprayInjection

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Next dispatch · May 2026 · Honest frequency: a few times a month

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